Endocrine Abstracts

Objectives: To evaluate the degree of control of atherogenic dyslipidaemia in patients with type 2 diabetes mellitus (T2DM).Methods: Retrospective cohort study which included patients with T2DM followed in a primary care setting. Patients were classified according to the following criteria: strict control of dyslipidaemia (LDL <100 mg/dl and triglycerides <150 mg/dl), partial control of dyslipidaemia (LDL ≥100 mg/dl or triglycerides ≥...

Myocardial gene expression and metabolism fluctuate over the course of the day, in association with changes in energy supply and demand. Recently, time-of-day-dependent oscillations in myocardial processes have been linked to the intrinsic cardiomyocyte circadian clock. Triiodothyronine (T3) is an important modulator of cardiac form and function. The genomic actions of T3 are triggered after its interaction with thyroid hormone nuclear receptors that ofte...

Introduction: Hypoglycemia is the most frequent metabolic complication observed in patients with type 2 diabetes mellitus (T2DM). Moreover, rare insulinomas are the most common cause of endogenous hyperinsulinemic hypoglycemia in adults. The coincidence of insulinoma in a patient with pre-existing T2DM is an extremely rare condition and there are few case reports in the medical literature.Case report: A 76-year-old woman diagnosed with T2DM 6 years ago, ...

Differentiated thyroid carcinoma is the most common endocrine malignant tumor. Papillary carcinoma frequency in our country is 80% of thyroid neoplasia. Papillary thyroid carcinoma usually metastasizes to cervical lymph. Metastases to distant organs are rare and most often affect the lungs, liver and bones. Despite of its anatomical proximity, metastasis parotid have not been described in the existing papillary carcinomas literature. We report a case of parotid gland metastasi...

Introduction: Some data suggest a favorable effect of glucagon-like peptide 1 (GLP1) on steato-hepatitis (SH) in type 2 diabetes. We report here a case of improvement of SH in a patient treated by liraglutide.Patients and methods: A 31-year-old woman presented type 2 diabetes. Her weight was 80 kg for 1.58 m (BMI=32 kg/m2). A treatment by liraglutide was initiated at 1.2 mg/day, percutaneously. A regular follow-up was performed with the record...

Introduction: The association of systemic lupus erythematosus (SLE) and dysthyroidism has been reported by several studies in a wide range of variability but studies focused on the influence of hypothyroidism on classic manifestations of SLE are scarce. Our purpose was to evaluate the prevalence of thyroid diseases in a cohort of SLE patients and the relevance of hypothyroidism with clinical and analytical parameters related to lupus.Methods/design: One ...

Introduction: Vitamin D insufficiency (D-INSUFF) has been associated with impaired immune response in human inmunodeficiency virus (HIV) patients and a worse prognosis in patients with liver fibrosis. Nevertheless, few studies have explored the influence of D-INSUFF in immunological response and liver parameters in HIV and hepatitis C virus co-infected patients (HIV/HCV) on long term highly active antiretroviral therapy (HAART) with successful immune and virological response. ...

Introduction: Pheochromocytoma multisystem crisis (PMC) is the most fulminant clinical expression of pheochromocytoma. The appropriate timing and judgment for the start of surgery and the adequate preoperative medical treatment are unclear. We report a case of PMC successfully treated with elective adrenalectomy after doxazosin blockade. The importance of an early biochemical diagnosis is discussed.Case report: A 47-year-old healthy man consulted for sud...

Introduction: Although the importance of disorders in glucose metabolism is well recognized in human immunodeficiency virus (HIV) infected patients; the clinical relevance of prediabetes in this population has been little studied. The aims of this observational study were to determine the prevalence of prediabetes in a cohort of HIV-infected patients on long term highly active antiretroviral therapy (HAART) and to assess whether this condition involves the appearance of partic...

Aim: To evaluate the efficacy and safety for first patients treated in our clinic with liraglutide.Methods: Retrospective study of patients who started treatment with liraglutide in the last year in our department. We collected data on age, years of evolution, chronic complications, previous treatment, physical examination, analytical parameters and side effects.Results: Fifty-four patients. Follow-up: 4–12 months. Mean age: 5...